Mucoadhesive In Situ Rectal Gel Loaded with Rifampicin: Strategy to Improve Bioavailability and Alleviate Liver Toxicity

Although it is a front-line in tuberculosis treatment, rifampicin (RF) exhibits poor oral bioavailability and hepatotoxicity.Rectal mucoadhesive and in situ rectal gels were developed to overcome drug drawbacks.A RF/polyethylene glycol 6000 co-precipitate was first prepared in different ratios.Based on the drug solubility, the selected ratio was in

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The Rental Property as a Direction of Transformation of Household Savings into a Development Resource of Region

The article is aimed at identifying possibilities of transformation of household savings into resource of development of region on the basis of an analysis of directions of investment of household funds and assessment of the real estate market in Ukraine.The main directions of investment of household funds are characterized as follows: investment O

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